Mesoporous Silica Nanoparticles with Dual Function ofAnti-Inflammatory and Lubrication for Rheumatoid Arthritis Treatment

MSN@DCF-HA was successfully prepared, exhibited slow drug release in acidic environments, and its anti-inflammation and joint lubrication exerted synergistic effects on RA rats without obvious toxicity. This work proposes a novel therapeutic strategy for rheumatoid arthritis.

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Publication Details

Journal
Current Drug Delivery
Published
2026-01-13
DOI
https://doi.org/10.2174/0115672018387431251127045211
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Mesoporous Silica Nanoparticles with Dual Function ofAnti-Inflammatory and Lubrication for Rheumatoid Arthritis Treatment

Hao Zhou, X Wang, Jinlong Xiao, Ying Zeng
Current Drug Delivery
Rheumatoid Arthritis Research and Therapies
article

Mesoporous Silica Nanoparticles with Dual Function ofAnti-Inflammatory and Lubrication for Rheumatoid Arthritis Treatment

Hao Zhou, X Wang, Jinlong Xiao, Ying Zeng
article en

Abstract

MSN@DCF-HA was successfully prepared, exhibited slow drug release in acidic environments, and its anti-inflammation and joint lubrication exerted synergistic effects on RA rats without obvious toxicity. This work proposes a novel therapeutic strategy for rheumatoid arthritis.

Current Drug DeliveryVol. 23
Bengbu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 80%
Rheumatoid Arthritis Research and Therapies
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Mesoporous Silica Nanoparticles with Dual Function ofAnti-Inflammatory and Lubrication for Rheumatoid Arthritis Treatment — Hao Zhou, X Wang, et al. · Current Drug Delivery (2026) | TGRS Research Map | TGRS