Impact of Seropositivity on Mortality and Extra-Articular Manifestations in Rheumatoid Arthritis: A Nationwide Propensity-Matched Cohort Study

This study highlights significant differences in several clinical outcomes between seropositive and seronegative RA patients. These findings highlight the more aggressive nature of seropositive disease and its extra-articular involvement and reinforce the importance of autoantibody status in prognostication and risk stratification for RA patients.

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Publication Details

Journal
Mediterranean Journal of Rheumatology
Published
2025-12-01
DOI
https://doi.org/10.31138/mjr.150425.smr
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Impact of Seropositivity on Mortality and Extra-Articular Manifestations in Rheumatoid Arthritis: A Nationwide Propensity-Matched Cohort Study

Reem Elmusa, Diala Alawneh, Omar S. Obeidat, Safwan Alomari et al.
Mediterranean Journal of Rheumatology
Rheumatoid Arthritis Research and Therapies
article

Impact of Seropositivity on Mortality and Extra-Articular Manifestations in Rheumatoid Arthritis: A Nationwide Propensity-Matched Cohort Study

Reem Elmusa, Diala Alawneh, Omar S. Obeidat, Safwan Alomari, Samah H. Al-Omari, Geran Maule, Abdallah Rayyan, Ahmad Alomari, Aseed Mestarihi, Qusai Alqudah, Osama Obeidat
article en

Abstract

This study highlights significant differences in several clinical outcomes between seropositive and seronegative RA patients. These findings highlight the more aggressive nature of seropositive disease and its extra-articular involvement and reinforce the importance of autoantibody status in prognostication and risk stratification for RA patients.

Mediterranean Journal of RheumatologyVol. 36(4)
University of Central Florida (US), Johns Hopkins University (US), Jordan University of Science and Technology (JO), AdventHealth Orlando (US), Johns Hopkins Medicine (US), University of Florida (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 24%
Rheumatoid Arthritis Research and Therapies
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