Association of major adverse cardiovascular events with the apnea-hypopnea index, desaturation severity parameters, and cardiac troponins in participants of the Akershus Sleep APnea cohort
In this 15-year follow-up, cTnI associated independently with higher MACE risk, whereas the AHI, desaturation parameters, and cTnT were not independent predictors. cTnI, especially when combined with AHI, was a stronger MACE predictor than cTnT. Provided our findings are validated in clinical OSA populations, the measurement of cTnI may be considered for cardiovascular risk stratification.
Authors
- T. Leppänen
- Ole Klungsøyr (ORCID: https://orcid.org/0000-0003-1952-4632)
- Tonje Caroline Øverby
- Sami Nikkonen (ORCID: https://orcid.org/0000-0003-0615-4118)
- Toril Dammen (ORCID: https://orcid.org/0000-0001-9383-2161)
- Fjola D. Sigurdardottir (ORCID: https://orcid.org/0000-0002-3497-2698)
- Juha Töyräs (ORCID: https://orcid.org/0000-0002-8035-1606)
- Torbjørn Omland (ORCID: https://orcid.org/0000-0002-6452-0369)
- Harald Hrubos‐Strøm (ORCID: https://orcid.org/0000-0003-0065-0145)
- Gunnar Einvik (ORCID: https://orcid.org/0000-0002-2235-6310)
- Erna Sif Arnardottir
- Henri Korkalainen
- Xin Feng
- Thea Thorshov
- Inger Hilde Nordhus
Institutions
- Reykjavík University (IS)
- Oslo University Hospital (NO)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- University of Eastern Finland (FI)
- University of Oslo (NO)
- Akershus University Hospital (NO)
- Kuopio University Hospital (FI)
- University of Bergen (NO)
Publication Details
- Journal
- SLEEP
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1093/sleep/zsag013
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00