Utility of a novel point-of-care test in detecting coronary artery disease following negative nuclear testing: a case series

This case series demonstrates the utility of POC-CAD as a non-invasive tool in the diagnostic pathway for patients with ongoing symptoms despite negative nuclear stress testing. The findings highlight limitations of nuclear stress testing, particularly its reduced sensitivity in multi-vessel disease. POC-CAD may help identify high-risk patients who would otherwise be missed, facilitating timely intervention. Integration of novel diagnostics such as POC-CAD into multimodal assessment strategies could improve accuracy and reduce diagnostic delays in CAD.