Class-Balanced Convolutional Neural Networks for Digital Mammography Image Classification in Breast Cancer Diagnosis

This study introduces a class-balanced Convolutional Neural Network (CNN) framework specifically designed for the binary classification of breast tumors in digital mammography. The proposed method systematically addresses the pervasive issue of class imbalance in medical imaging datasets by implementing advanced dataset balancing strategies, which resulted in a significant reduction in false negatives that is critical in early breast cancer detection. The proposed architecture is designed for high-resolution mammograms and employs regularization techniques, such as dropout and L2 weight decay, which are intended to enhance generalization and reduce the risk of overfitting. Comprehensive data augmentation and normalization further enhance the model’s robustness and adaptability to real-world clinical variability. Evaluated on the MIAS dataset, our balanced CNN achieved an accuracy of 98.84%, exhibiting both sensitivity and overall reliability. This work demonstrates that a class-balanced CNN can deliver both high diagnostic accuracy and computational efficiency, indicating potential for future use in clinical screening workflows. The system’s ability to minimize diagnostic errors and support radiologists with reliable, data-driven predictions represents an exploratory step toward improving automated breast cancer detection.

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Publication Details

Journal
Electronics
Published
2026-01-22
DOI
https://doi.org/10.3390/electronics15020486
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
0.00
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article

Class-Balanced Convolutional Neural Networks for Digital Mammography Image Classification in Breast Cancer Diagnosis

Nikolaos Laskaris, Evangelos Pallis, Paraskevi Zacharia, Evangelos Mavropoulos
Electronics
AI in cancer detection
article

Class-Balanced Convolutional Neural Networks for Digital Mammography Image Classification in Breast Cancer Diagnosis

Nikolaos Laskaris, Evangelos Pallis, Paraskevi Zacharia, Evangelos Mavropoulos
article en

Abstract

This study introduces a class-balanced Convolutional Neural Network (CNN) framework specifically designed for the binary classification of breast tumors in digital mammography. The proposed method systematically addresses the pervasive issue of class imbalance in medical imaging datasets by implementing advanced dataset balancing strategies, which resulted in a significant reduction in false negatives that is critical in early breast cancer detection. The proposed architecture is designed for high-resolution mammograms and employs regularization techniques, such as dropout and L2 weight decay, which are intended to enhance generalization and reduce the risk of overfitting. Comprehensive data augmentation and normalization further enhance the model’s robustness and adaptability to real-world clinical variability. Evaluated on the MIAS dataset, our balanced CNN achieved an accuracy of 98.84%, exhibiting both sensitivity and overall reliability. This work demonstrates that a class-balanced CNN can deliver both high diagnostic accuracy and computational efficiency, indicating potential for future use in clinical screening workflows. The system’s ability to minimize diagnostic errors and support radiologists with reliable, data-driven predictions represents an exploratory step toward improving automated breast cancer detection.

ElectronicsVol. 15(2)
University of West Attica (GR)
Good health and well-being
Openalex Percentile: Top 80%
AI in cancer detection
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