Identifying druggable gene-related biomarkers in intervertebral disc degeneration through transcriptome sequencing and mendelian randomization analysis

This study constructed a diagnostic model and identified BPI and CTSG as potential biomarkers for IDD, providing new insights into IDD treatment.

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Publication Details

Journal
Frontiers in Genetics
Published
2026-01-22
DOI
https://doi.org/10.3389/fgene.2026.1627091
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
Field-Weighted Citation Impact
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article

Identifying druggable gene-related biomarkers in intervertebral disc degeneration through transcriptome sequencing and mendelian randomization analysis

Keping Wang
Frontiers in Genetics
Spine and Intervertebral Disc Pathology
article

Identifying druggable gene-related biomarkers in intervertebral disc degeneration through transcriptome sequencing and mendelian randomization analysis

Keping Wang
article en

Abstract

This study constructed a diagnostic model and identified BPI and CTSG as potential biomarkers for IDD, providing new insights into IDD treatment.

Frontiers in GeneticsVol. 17
Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Good health and well-being
Openalex Percentile: Top 80%
Spine and Intervertebral Disc Pathology
DOIOpen Access PDFOpenAlex
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