Impact of Toll/Interleukin-1 Receptor Domain Protein C on Mesenchymal Stem Cells Mitochondrial Protein Expression: A Proteomic Study
TCP-C intervention leads to a series of differentially expressed proteins in MSC mitochondria, which are involved in several functional clusters, including oxidative phosphorylation, respiratory electron transport, the tricarboxylic acid cycle, glyoxylate and dicarboxylate metabolism, branched-chain amino acid catabolism, and cristae formation.
Authors
- Xia Lei (ORCID: https://orcid.org/0000-0002-2077-587X)
- Yuxing Wang (ORCID: https://orcid.org/0000-0003-3079-5572)
- Dongyang Guo
- Jiaqi Fang
Institutions
- Zhejiang University (CN)
Publication Details
- Journal
- Current Molecular Medicine
- Published
- 2026-01-13
- DOI
- https://doi.org/10.2174/0115665240411988251128121911
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00