Surgical management of giant craniopharyngiomas: expanded endoscopic endonasal or transcranial approach?

Expanded EEA is associated with a similar gross-total resection rate, greater visual improvement, and better hypothalamic and endocrinological function compared with traditional TCA. Although not statistically significant, EEA was associated with a higher risk for postoperative CSF leaks. These data favor the view that EEA is a safe and effective surgical modality, providing a viable alternative to TCA for GCPs.

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Publication Details

Journal
Journal of neurosurgery
Published
2025-12-01
DOI
https://doi.org/10.3171/2025.8.jns25138
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
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article

Surgical management of giant craniopharyngiomas: expanded endoscopic endonasal or transcranial approach?

Bin Tang, Yanyan Zhu, Jian Duan, YouYuan Bao et al.
Journal of neurosurgery
Pituitary Gland Disorders and Treatments
article

Surgical management of giant craniopharyngiomas: expanded endoscopic endonasal or transcranial approach?

Bin Tang, Yanyan Zhu, Jian Duan, YouYuan Bao, ShenHao Xie, Zhongzheng Gao, Danke Shen, Jie Wu, Tao Hong, Jun Fu, Zihan Yin
article en

Abstract

Expanded EEA is associated with a similar gross-total resection rate, greater visual improvement, and better hypothalamic and endocrinological function compared with traditional TCA. Although not statistically significant, EEA was associated with a higher risk for postoperative CSF leaks. These data favor the view that EEA is a safe and effective surgical modality, providing a viable alternative to TCA for GCPs.

Journal of neurosurgery
Nanchang University (CN), Capital Medical University (CN), Beijing Tian Tan Hospital (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Integrated Chinese Medicine (China) (HK), First Affiliated Hospital of Nanchang University (CN)
Good health and well-being
Openalex Percentile: Top 27%
Pituitary Gland Disorders and Treatments
DOISourceOpenAlex
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Surgical management of giant craniopharyngiomas: expanded endoscopic endonasal or transcranial approach? — Bin Tang, Yanyan Zhu, et al. · Journal of neurosurgery (2025) | TGRS Research Map | TGRS