Fractional ethanol precipitation modulates the structure and function of Coprinus comatus mycelial polysaccharides: alleviation of DSS-induced injury in Caco-2 cells via regulation of mitochondrial function

This study elucidates the regulatory effect of ethanol precipitation concentration on the physicochemical properties and functional activities of CC mycelial polysaccharides, and reveals the potential of CCPJ-80 to ameliorate ulcerative colitis by modulating oxidative stress and mitochondrial function pathways, providing a scientific basis for developing CCPJ as a functional food or therapeutic agent.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-01-22
DOI
https://doi.org/10.3389/fnut.2026.1743246
Primary Topic
Polysaccharides and Plant Cell Walls
Type
article
Field-Weighted Citation Impact
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article

Fractional ethanol precipitation modulates the structure and function of Coprinus comatus mycelial polysaccharides: alleviation of DSS-induced injury in Caco-2 cells via regulation of mitochondrial function

Tao Gu, Ruijie Chen, Zhun Xiang, Shaofeng Wei
Frontiers in Nutrition
Polysaccharides and Plant Cell Walls
article

Fractional ethanol precipitation modulates the structure and function of Coprinus comatus mycelial polysaccharides: alleviation of DSS-induced injury in Caco-2 cells via regulation of mitochondrial function

Tao Gu, Ruijie Chen, Zhun Xiang, Shaofeng Wei
article en

Abstract

This study elucidates the regulatory effect of ethanol precipitation concentration on the physicochemical properties and functional activities of CC mycelial polysaccharides, and reveals the potential of CCPJ-80 to ameliorate ulcerative colitis by modulating oxidative stress and mitochondrial function pathways, providing a scientific basis for developing CCPJ as a functional food or therapeutic agent.

Frontiers in NutritionVol. 13
Guizhou Academy of Agricultural Sciences (CN), Ministry of Education (IR)
Openalex Percentile: Top 79%
Polysaccharides and Plant Cell Walls
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