Protective Role of Glibenclamide and Magnesium Sulfate in FructoseinducedType 2 Diabetes Mellitus

Both glibenclamide and magnesium sulfate demonstrated significant protective and therapeutic effects against fructose-induced T2DM. Their combined ability to restore metabolic balance, enhance antioxidant capacity, and correct trace element deficiencies suggests potential clinical relevance of magnesium supplementation as an adjunct therapy in the management of type 2 diabetes mellitus.

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Publication Details

Journal
Current Pharmaceutical Biotechnology
Published
2026-01-12
DOI
https://doi.org/10.2174/0113892010396082251107094426
Primary Topic
Diet, Metabolism, and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Protective Role of Glibenclamide and Magnesium Sulfate in FructoseinducedType 2 Diabetes Mellitus

Kousar Yasmeen, Zia Ur Rehman, Syed M. Shahid, Sarah Akhtar et al.
Current Pharmaceutical Biotechnology
Diet, Metabolism, and Disease
article

Protective Role of Glibenclamide and Magnesium Sulfate in FructoseinducedType 2 Diabetes Mellitus

Kousar Yasmeen, Zia Ur Rehman, Syed M. Shahid, Sarah Akhtar, Syeda Nuzhat Fatima Zaidi, Sultan M. Alshahrani
article en

Abstract

Both glibenclamide and magnesium sulfate demonstrated significant protective and therapeutic effects against fructose-induced T2DM. Their combined ability to restore metabolic balance, enhance antioxidant capacity, and correct trace element deficiencies suggests potential clinical relevance of magnesium supplementation as an adjunct therapy in the management of type 2 diabetes mellitus.

Current Pharmaceutical BiotechnologyVol. 27
Eastern Institute of Technology (NZ), Federal Urdu University (PK), Te Pūkenga (NZ), King Khalid University (SA)
Openalex Percentile: Top 81%
Diet, Metabolism, and Disease
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