EUS-guided gastroenterostomy for benign gastric outlet obstruction: Clinical and technical outcomes from a multicenter cohort study
Abstract Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is emerging as a minimally invasive alternative for benign gastric outlet obstruction (GOO). This study evaluated its safety, efficacy, and long-term outcomes. This international, multicenter retrospective study included 72 patients who underwent EUS-GE for benign GOO across 13 centers. Clinical success was defined as ability to tolerate solid food based on the GOO scoring system. Secondary outcomes included technical success and adverse events (AEs). Technical success was achieved in 97% of cases. Ability to tolerate solid food improved significantly, from 4% pre-procedure to 90% at 60 days post-procedure (<i>P</i> < 0.00001). Mean time to oral intake was 20.1 hours. AEs were mild, occurring in 6% intra-procedurally and 10% post-procedurally. Mean follow-up duration was 426.3 days. EUS-GE demonstrates high technical and clinical success rates with a favorable safety profile for benign GOO, offering a promising alternative to traditional surgical approaches.
Authors
- Jahnvi Dhar (ORCID: https://orcid.org/0000-0002-6929-4276)
- Farimah Fayyaz (ORCID: https://orcid.org/0000-0002-5692-0370)
- Enad Dawod
- Kavel Visrodia (ORCID: https://orcid.org/0000-0002-2762-0889)
- Jayanta Samanta (ORCID: https://orcid.org/0000-0002-9277-5086)
- Kartik Sampath
- A. Larghi
- SriHari Mahadev (ORCID: https://orcid.org/0000-0002-4123-3922)
- Kate E. Johnson
- Carlos Robles‐Medranda (ORCID: https://orcid.org/0000-0003-2434-3369)
- Amrita Sethi
- Irene Cottone
- Michel Al Mardini
- Jorge Vargas
- David L. Carr-Locke
- Anam Rizvi
- Martha Arevalo
- E. Forti (ORCID: https://orcid.org/0000-0003-1725-5344)
- Mouen A. Khashab
- Working Group
- Mark Hanscom
- Kamal Hassan
- Reem Z Sharaiha
- Juan Alcivar Vasquez
- Laith Eyad Baqain
Institutions
- NewYork–Presbyterian Hospital (US)
- Johns Hopkins University (US)
- Cornell University (US)
- Columbia University Irving Medical Center (US)
- King Hussein Medical Center (JO)
- Agostino Gemelli University Polyclinic (IT)
- Costa Rican Department of Social Security (CR)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Presbyterian Hospital (US)
- Instituto Ecuatoriano de Enfermedades Digestivas (EC)
- Kennedy Clinic Hospital (EC)
- Post Graduate Institute of Medical Education and Research (IN)
Publication Details
- Journal
- Endoscopy International Open
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1055/a-2778-5386
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00