U-Shaped Lipid-CVD Links in Older Adults

U/L-shaped associations of LDL-C and HDL-C with CVD risk in older adults underscore the importance of maintaining lipids within an optimal range. This distinct "Goldilocks zone" is associated with minimized risk and highlights current guideline limitations.

Authors

Institutions

Publication Details

Journal
JACC Advances
Published
2026-01-22
DOI
https://doi.org/10.1016/j.jacadv.2025.102544
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

U-Shaped Lipid-CVD Links in Older Adults

Chunjiang Pan, Miao Liu, Shanshan Yang, Yao He et al.
JACC Advances
Lipoproteins and Cardiovascular Health
article

U-Shaped Lipid-CVD Links in Older Adults

Chunjiang Pan, Miao Liu, Shanshan Yang, Yao He, Xiaoxin Ye, Yueting Shi, Jing Zeng, Wenchang Wang, Shimin Chen, Yanhao Wan, Jianhua Wang, Shengyan Du
article en

Abstract

U/L-shaped associations of LDL-C and HDL-C with CVD risk in older adults underscore the importance of maintaining lipids within an optimal range. This distinct "Goldilocks zone" is associated with minimized risk and highlights current guideline limitations.

JACC AdvancesVol. 5(2)
Chinese PLA General Hospital (CN), Chinese General Hospital College of Nursing and Liberal Arts (PH), Beijing Geriatric Hospital (CN), People's Liberation Army No. 150 Hospital (CN), Chinese People’s Liberation Army 263 hospital (CN)
Zero hunger
Openalex Percentile: Top 80%
Lipoproteins and Cardiovascular Health
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.