Triple-helix crosslinked hydrogels with sol-gel transition in response to collagen model peptides

Abstract This study developed a thermoresponsive hydrogel crosslinked by collagen-motif triple helix and analyzed the sol-gel transition property and the effect of additional collagen model peptides (CMPs). The CMPs grafted 4arm-Poly(ethylene glycol) gel can be controlled by the CMPs hetero triple helix formation, amino acid sequence variation, and additional single-strand CMPs.

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Publication Details

Journal
Chemistry Letters
Published
2026-01-21
DOI
https://doi.org/10.1093/chemle/upag009
Primary Topic
Collagen: Extraction and Characterization
Type
article
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article

Triple-helix crosslinked hydrogels with sol-gel transition in response to collagen model peptides

Kazuki Yoshida, Michiya Matsusaki
Chemistry Letters
Collagen: Extraction and Characterization
article

Triple-helix crosslinked hydrogels with sol-gel transition in response to collagen model peptides

Kazuki Yoshida, Michiya Matsusaki
article en

Abstract

Abstract This study developed a thermoresponsive hydrogel crosslinked by collagen-motif triple helix and analyzed the sol-gel transition property and the effect of additional collagen model peptides (CMPs). The CMPs grafted 4arm-Poly(ethylene glycol) gel can be controlled by the CMPs hetero triple helix formation, amino acid sequence variation, and additional single-strand CMPs.

Chemistry LettersVol. 55(2)
The University of Osaka (JP)
Openalex Percentile: Top 82%
Collagen: Extraction and Characterization
DOISourceOpenAlex
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Triple-helix crosslinked hydrogels with sol-gel transition in response to collagen model peptides — Kazuki Yoshida, Michiya Matsusaki · Chemistry Letters (2026) | TGRS Research Map | TGRS