Pre-HCT Resistome Disruption Predicts ESBL Gene Expansion in Pediatric Transplant Recipients: A Prospective Multi-Center Study
Infections are the leading cause of death after HCT, and recently the role of the gut microbiome in harboring dangerous bacteria has been highlighted. This study aims to understand multidrug resistant bacteria changes in the gut microbiome early after HCT.
Authors
- Davide Leardini (ORCID: https://orcid.org/0000-0002-4673-5876)
- Eileen J. Klein
- Marygrace Duggar
- Randall T. Hayden (ORCID: https://orcid.org/0000-0002-3073-4115)
- Qidong Jia
- Marek Ussowicz (ORCID: https://orcid.org/0000-0001-5725-4835)
- Elisa Margolis (ORCID: https://orcid.org/0000-0001-6217-0564)
- Jose Ferrolino (ORCID: https://orcid.org/0000-0003-4008-5507)
- Jowita Frączkiewicz (ORCID: https://orcid.org/0000-0002-8467-8788)
- Edoardo Muratore (ORCID: https://orcid.org/0000-0001-6954-3140)
- Yulin Sun
- Gabriela A. Marón
- Maura Faraci
- Hana Hakim
- Simone Cesaro
- Anju Cherian
- Ronald Dallas
- Janet Englund
- Joshua Wolf
- Li Tang
- Riccardo Masetti
Institutions
- St. Jude Children's Research Hospital (US)
- Cleveland Clinic (US)
- University of Tennessee Health Science Center (US)
- Istituto Giannina Gaslini (IT)
- Wroclaw Medical University (PL)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Seattle Children's Hospital (US)
- Azienda USL di Bologna (IT)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-22
- DOI
- https://doi.org/10.64898/2026.01.20.26344466
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00