Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth Outcomes: A Nationwide Cohort Study

In this nationwide cohort, discontinuation of statins at pregnancy was not associated with increased maternal cardiovascular risk, including among high-risk women. Secondary analyses suggested differences in fetal outcomes between groups; however, these findings should be interpreted cautiously given the observational design.

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Publication Details

Journal
Circulation
Published
2026-01-23
DOI
https://doi.org/10.1161/circulationaha.125.078919
Primary Topic
Cardiovascular Issues in Pregnancy
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth Outcomes: A Nationwide Cohort Study

Hyesung Lee, HyunJoo Lim, Yongtai Cho, Gi Hong Choi et al.
Circulation
Cardiovascular Issues in Pregnancy
article

Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth Outcomes: A Nationwide Cohort Study

Hyesung Lee, HyunJoo Lim, Yongtai Cho, Gi Hong Choi, Juyoung Shin, Danbee Kang, Eun-Young Choi
article en

Abstract

In this nationwide cohort, discontinuation of statins at pregnancy was not associated with increased maternal cardiovascular risk, including among high-risk women. Secondary analyses suggested differences in fetal outcomes between groups; however, these findings should be interpreted cautiously given the observational design.

CirculationVol. 153(7)
Kangwon National University (KR), Samsung Medical Center (KR), Karolinska Institutet (SE), Sungkyunkwan University (KR)
Good health and well-being
Openalex Percentile: Top 81%
Cardiovascular Issues in Pregnancy
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