Histologic margin involvement by cutaneous basal cell carcinoma stroma: a retrospective cohort study for residual or recurrent carcinoma

Stromal margin involvement in non-superficial BCCs is rarely associated with residual or recurrent carcinoma. Adverse outcomes were confined to tumors containing a superficial component, highlighting biologic heterogeneity among BCC subtypes. These findings suggest that routine re-excision may be unnecessary for stromal-margin-positive BCCs lacking a superficial component and support more selective, subtype-informed management.

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Publication Details

Journal
Journal of Clinical Pathology
Published
2026-01-23
DOI
https://doi.org/10.1136/jcp-2025-210475
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Histologic margin involvement by cutaneous basal cell carcinoma stroma: a retrospective cohort study for residual or recurrent carcinoma

Danielle R Rinck, Steven R. Tahan
Journal of Clinical Pathology
Nonmelanoma Skin Cancer Studies
article

Histologic margin involvement by cutaneous basal cell carcinoma stroma: a retrospective cohort study for residual or recurrent carcinoma

Danielle R Rinck, Steven R. Tahan
article en

Abstract

Stromal margin involvement in non-superficial BCCs is rarely associated with residual or recurrent carcinoma. Adverse outcomes were confined to tumors containing a superficial component, highlighting biologic heterogeneity among BCC subtypes. These findings suggest that routine re-excision may be unnecessary for stromal-margin-positive BCCs lacking a superficial component and support more selective, subtype-informed management.

Journal of Clinical PathologyVol. 79(4)
Beth Israel Deaconess Medical Center (US)
Openalex Percentile: Top 80%
Nonmelanoma Skin Cancer Studies
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