Gut microbial alterations associated with the exacerbation of experimental autoimmune uveitis in PGRN-deficient mice
Our results showed that PGRN plays a protective role in EAU, and the significant changes in the gut microbiome may be associated with the exacerbation of inflammation in the PGRN-deficient EAU mice.
Authors
- Chaokui Wang
- Song Zhang (ORCID: https://orcid.org/0000-0003-0570-1909)
- Wenjun Zhou
Institutions
- State Key Laboratory of Pollution Control and Resource Reuse (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-23
- DOI
- https://doi.org/10.3389/fimmu.2026.1641755
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre Scientifique et Technique du Bâtiment