Prognostic immunological implications of OX40L expression in the tumor microenvironment of melanoma
OX40L protein expression is a heterogeneous but prominent feature of the melanoma microenvironment, with cell type-specific expression patterns that include regulatory T cells. An exploratory association was seen between myeloid OX40L expression and clinical outcome, warranting further investigation.
Authors
- Emmanuela Riklin-Nahmias
- Sonia Mendlovic
- Ayelet Avraham (ORCID: https://orcid.org/0000-0003-2451-886X)
- Nona Ofek
- Susanna Feldman
- Adi Pollak-Moseri
- Liliana Elkis
- Baseem Da’ana
- Raya Leibowitz
Institutions
- Medical University of Graz (AT)
- Shaqra University (SA)
- Barzilai Medical Center (IL)
- Muthén & Muthén (United States) (US)
- Post Graduate Medical Institute (PK)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-23
- DOI
- https://doi.org/10.3389/fimmu.2026.1745742
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00