Quantification of DNA Methylation for Diagnosis and Monitoring of Hepatocellular Carcinoma

HBMV is a sensitive and biologically grounded biomarker for HCC diagnosis, prognosis, and real-time disease monitoring. These findings support further prospective evaluation of HBMV as a noninvasive tool for clinical surveillance and assessment of treatment response.

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Publication Details

Journal
Journal of the American College of Surgeons
Published
2026-01-23
DOI
https://doi.org/10.1097/xcs.0000000000001792
Primary Topic
Epigenetics and DNA Methylation
Type
article
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article

Quantification of DNA Methylation for Diagnosis and Monitoring of Hepatocellular Carcinoma

Steven J. Hughes, Rohan Ganguli, ALI ZARRINPAR, Salar Javanshir et al.
Journal of the American College of Surgeons
Epigenetics and DNA Methylation
article

Quantification of DNA Methylation for Diagnosis and Monitoring of Hepatocellular Carcinoma

Steven J. Hughes, Rohan Ganguli, ALI ZARRINPAR, Salar Javanshir, Anastasia Chambers, Ilyas Sahin, Pavan Iyengar, Sergio Duarte, Isabella Angeli-Pahim, Iulia Maria Smarandache
article en

Abstract

HBMV is a sensitive and biologically grounded biomarker for HCC diagnosis, prognosis, and real-time disease monitoring. These findings support further prospective evaluation of HBMV as a noninvasive tool for clinical surveillance and assessment of treatment response.

Journal of the American College of SurgeonsVol. 242(4)
University of Florida Health (US), Massachusetts General Hospital (US), Center for Cancer Research (US)
Good health and well-being
Openalex Percentile: Top 80%
Epigenetics and DNA Methylation
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Quantification of DNA Methylation for Diagnosis and Monitoring of Hepatocellular Carcinoma — Steven J. Hughes, Rohan Ganguli, et al. · Journal of the American College of Surgeons (2026) | TGRS Research Map | TGRS