Radiation-induced meningiomas: A systematic review and meta-analysis of 927 meningiomas

High- and low-dose cranial radiation therapy can differentially influence the latency and grade of RIM, with higher dose CRT associated with earlier onset and more atypical tumors RIM screening may be warranted in individuals with an early exposure to cranial radiation given the increased risk of developing secondary neoplasms. These findings support structured long-term magnetic resonance imaging surveillance for survivors of childhood cranial irradiation, with risk adapted follow-up protocols to enable earlier detection and management.

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Publication Details

Journal
Surgical Neurology International
Published
2026-01-23
DOI
https://doi.org/10.25259/sni_1037_2025
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Radiation-induced meningiomas: A systematic review and meta-analysis of 927 meningiomas

Dheerendra Prasad, Tyler V. Schrand, Sarthak Sinha, Rohil Shekher et al.
Surgical Neurology International
Meningioma and schwannoma management
article

Radiation-induced meningiomas: A systematic review and meta-analysis of 927 meningiomas

Dheerendra Prasad, Tyler V. Schrand, Sarthak Sinha, Rohil Shekher, Neil D. Almeida, Michael T. Milano, Mengyu Fang, Harshini K. Cheruvu, Victor Goulenko, Venkatesh Madhugiri, Julia Rupp
article en

Abstract

High- and low-dose cranial radiation therapy can differentially influence the latency and grade of RIM, with higher dose CRT associated with earlier onset and more atypical tumors RIM screening may be warranted in individuals with an early exposure to cranial radiation given the increased risk of developing secondary neoplasms. These findings support structured long-term magnetic resonance imaging surveillance for survivors of childhood cranial irradiation, with risk adapted follow-up protocols to enable earlier detection and management.

Surgical Neurology InternationalVol. 17
Tulane University (US), Roswell Park Comprehensive Cancer Center (US), Cornell University (US), University of Rochester Medical Center (US), Jacobs Institute (US)
Reduced inequalities
Openalex Percentile: Top 80%
Meningioma and schwannoma management
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