Multiple Maternal Chronic Conditions and Risk of Severe Neonatal Morbidity and Mortality

In this study, risks of SNM-M increased with an increasing number of preexisting maternal chronic conditions. These findings suggest that women and adolescents with MCC may benefit from preconception counseling to optimize chronic disease management, monitoring in pregnancy for earlier identification of complications, and enhanced newborn supports.

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Publication Details

Journal
JAMA Network Open
Published
2026-01-23
DOI
https://doi.org/10.1001/jamanetworkopen.2025.55558
Primary Topic
Chronic Disease Management Strategies
Type
article
Field-Weighted Citation Impact
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article

Multiple Maternal Chronic Conditions and Risk of Severe Neonatal Morbidity and Mortality

Hilary K. Brown, Simone N. Vigod, Jannah Wigle, Eyal Cohen et al.
JAMA Network Open
Chronic Disease Management Strategies
article

Multiple Maternal Chronic Conditions and Risk of Severe Neonatal Morbidity and Mortality

Hilary K. Brown, Simone N. Vigod, Jannah Wigle, Eyal Cohen, Sonia M. Grandi, Walter P. Wodchis, JG Ray, Cindy-Lee Dennis, Laura C. Rosella, Catherine Varner, Kinwah Fung
article en

Abstract

In this study, risks of SNM-M increased with an increasing number of preexisting maternal chronic conditions. These findings suggest that women and adolescents with MCC may benefit from preconception counseling to optimize chronic disease management, monitoring in pregnancy for earlier identification of complications, and enhanced newborn supports.

JAMA Network OpenVol. 9(1)
Mount Sinai Hospital (CA), University of Toronto (CA), Lunenfeld-Tanenbaum Research Institute (CA), Scarborough Health Network (CA), Trillium Health Centre (CA), Hospital for Sick Children (CA), Women's College Hospital (CA), Public Health Ontario (CA), Institute for Clinical Evaluative Sciences (CA), Unity Health Toronto
Good health and well-being
Openalex Percentile: Top 80%
Chronic Disease Management Strategies
DOIOpen Access PDFOpenAlex
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Multiple Maternal Chronic Conditions and Risk of Severe Neonatal Morbidity and Mortality — Hilary K. Brown, Simone N. Vigod, et al. · JAMA Network Open (2026) | TGRS Research Map | TGRS