Letermovir Prophylaxis for Cytomegalovirus Infection in Adult Allogeneic Stem Cell Transplantation: A Retrospective Analysis From a Lower-Middle-Income Country

No statistically significant differences were observed between innovator and bioequivalent letermovir formulations with respect to safety or CMV outcomes. Availability of a cost-effective bioequivalent formulation may substantially expand access to CMV prophylaxis, supporting improved transplant outcomes in high-burden LMICs.

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Publication Details

Journal
Cureus
Published
2026-01-23
DOI
https://doi.org/10.7759/cureus.102136
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Letermovir Prophylaxis for Cytomegalovirus Infection in Adult Allogeneic Stem Cell Transplantation: A Retrospective Analysis From a Lower-Middle-Income Country

Swati Bhayana, Vikas Dua, Anusha Swaminathan, Nikhil Kumar et al.
Cureus
Cytomegalovirus and herpesvirus research
article

Letermovir Prophylaxis for Cytomegalovirus Infection in Adult Allogeneic Stem Cell Transplantation: A Retrospective Analysis From a Lower-Middle-Income Country

Swati Bhayana, Vikas Dua, Anusha Swaminathan, Nikhil Kumar, Neha Rastogi, Suyash Bharat, Ashutosh Panda, Kapil Chahal, Anindita Paul, Shrinidhi Nathany, Onyeaghala Chizaram, Rachit Agrawal, Rahul Bhargava
article en

Abstract

No statistically significant differences were observed between innovator and bioequivalent letermovir formulations with respect to safety or CMV outcomes. Availability of a cost-effective bioequivalent formulation may substantially expand access to CMV prophylaxis, supporting improved transplant outcomes in high-burden LMICs.

CureusVol. 18(1)
University of Port Harcourt Teaching Hospital (NG), Shree Guru Gobind Singh Tricentenary University (IN), Fortis Memorial Research Institute (IN), Zydus Lifesciences Limited (India) (IN), International Centre for Genetic Engineering and Biotechnology (IN)
No poverty
Openalex Percentile: Top 80%
Cytomegalovirus and herpesvirus research
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