<scp>Y181C</scp> ‐associated virologic failure during long‐acting injectable cabotegravir/Rilpivirine in a patient engaged in intensive intravenous Chemsex

This case highlights that unexpected resistance can emerge during adequately administered LA-CAB/RPV therapy. Careful clinical evaluation is warranted when virologic failure occurs, particularly in the presence of extreme behavioural or physiological stressors.

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Publication Details

Journal
HIV Medicine
Published
2026-01-23
DOI
https://doi.org/10.1111/hiv.70199
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Y181C ‐associated virologic failure during long‐acting injectable cabotegravir/Rilpivirine in a patient engaged in intensive intravenous Chemsex

Santiago Melón, Victor Asensi, Rebeca Cabo, María Rivas‐Carmenado
HIV Medicine
HIV/AIDS drug development and treatment
article

Y181C ‐associated virologic failure during long‐acting injectable cabotegravir/Rilpivirine in a patient engaged in intensive intravenous Chemsex

Santiago Melón, Victor Asensi, Rebeca Cabo, María Rivas‐Carmenado
article en

Abstract

This case highlights that unexpected resistance can emerge during adequately administered LA-CAB/RPV therapy. Careful clinical evaluation is warranted when virologic failure occurs, particularly in the presence of extreme behavioural or physiological stressors.

HIV Medicine
Hospital Universitario Central de Asturias (ES), Instituto de Investigación Sanitaria del Principado de Asturias (ES)
Good health and well-being
Openalex Percentile: Top 78%
HIV/AIDS drug development and treatment
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