Increased C‐reactive protein is associated with corneal nerve loss and painful neuropathic symptoms in Type 2 diabetes mellitus

Elevated CRP is associated with small nerve fiber loss and positive neuropathic symptoms in T2D. These findings suggest that CRP may help identify individuals with inflammation-driven DPN who could benefit from targeted interventions.

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Publication Details

Journal
Journal of Diabetes Investigation
Published
2026-01-23
DOI
https://doi.org/10.1111/jdi.70246
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00
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article

Increased C‐reactive protein is associated with corneal nerve loss and painful neuropathic symptoms in Type 2 diabetes mellitus

Hamda Ali, Tania Bibi, Einas Elgassim, Youssra Dakroury et al.
Journal of Diabetes Investigation
Ocular Surface and Contact Lens
article

Increased C‐reactive protein is associated with corneal nerve loss and painful neuropathic symptoms in Type 2 diabetes mellitus

Hamda Ali, Tania Bibi, Einas Elgassim, Youssra Dakroury, Yousuf Al‐Ansari, Hoda Gad, Adnan Khan, Mashhood A. Siddique, Stephen Lawrence Atkin, Mahmoud Zirie, Maya Deeb, Iuliia Salivon, Abeer M. M. El Shewehy, Sidra Abdulshakoor, Sara H. Khalfalla, Iynas S. A. Elamin, Abeer T. H. AlZawqari, Dorothy J. Quadros, Mohammad Qasim Minhas, Rayaz A. Malik, Lina H. M. Ahmed, Yara Ismail, Mariam A. O. Al‐Malaheem, Georgios Ponirakis, Ibrahim Al‐Janahi, Jenneth M. Concepcion, Ioannis N. Petropoulos, Hadeel B. Zaghloul
article en

Abstract

Elevated CRP is associated with small nerve fiber loss and positive neuropathic symptoms in T2D. These findings suggest that CRP may help identify individuals with inflammation-driven DPN who could benefit from targeted interventions.

Journal of Diabetes InvestigationVol. 17(3)
Manchester Metropolitan University (GB), Royal College of Surgeons in Ireland - Bahrain (BH), Manchester Academic Health Science Centre (GB), University of Manchester (GB), Hamad General Hospital (QA), Weill Cornell Medical College in Qatar (QA), Hamad Medical Corporation (QA), Qatar Foundation (QA)
Good health and well-being
Openalex Percentile: Top 81%
Ocular Surface and Contact Lens
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