Different dosing regimens for chronic knee osteoarthritis (KOA) pain management: A pooled analysis on celecoxib

Celecoxib 100 mg BID and 200 mg OD are both effective for OA pain relief, in moderate and severe pain. Findings suggest 200 mg OD may confer an advantage in patients with severe baseline pain in the long-term treatment (week 6).

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Publication Details

Journal
Aging Clinical and Experimental Research
Published
2026-01-23
DOI
https://doi.org/10.1007/s40520-025-03302-2
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Different dosing regimens for chronic knee osteoarthritis (KOA) pain management: A pooled analysis on celecoxib

Ernest Choy, Srinivasan Venugopal, Chris Walker, Raffaella Maria Rita Chiaese et al.
Aging Clinical and Experimental Research
Inflammatory mediators and NSAID effects
article

Different dosing regimens for chronic knee osteoarthritis (KOA) pain management: A pooled analysis on celecoxib

Ernest Choy, Srinivasan Venugopal, Chris Walker, Raffaella Maria Rita Chiaese, Egbert Biesheuvel, Nicholas Fuggle, Jean-Yves Reginster, Sagar Suresh Kumbhar
article en

Abstract

Celecoxib 100 mg BID and 200 mg OD are both effective for OA pain relief, in moderate and severe pain. Findings suggest 200 mg OD may confer an advantage in patients with severe baseline pain in the long-term treatment (week 6).

Aging Clinical and Experimental ResearchVol. 38(1)
King Saud University (SA), MRC Lifecourse Epidemiology Unit (GB), Tris Pharma (United States) (US), University of Southampton (GB), Cardiff University (GB)
Good health and well-being
Openalex Percentile: Top 78%
Inflammatory mediators and NSAID effects
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Different dosing regimens for chronic knee osteoarthritis (KOA) pain management: A pooled analysis on celecoxib — Ernest Choy, Srinivasan Venugopal, et al. · Aging Clinical and Experimental Research (2026) | TGRS Research Map | TGRS