An integrated deep learning framework leveraging NASNet and vision transformer with MixProcessing for accurate and precise diagnosis of lung diseases
Lung diseases such as pneumonia, tuberculosis, COVID-19, and lung cancer remain significant global health challenges that demand rapid and accurate diagnosis to improve patient outcomes. This study proposes NASNet-ViT, a novel deep learning framework that integrates the powerful convolutional feature extraction of NASNet with the global attention mechanisms of the Vision Transformer (ViT). To enhance diagnostic precision, a multi-stage preprocessing pipeline, termed MixProcessing, is introduced, combining wavelet transform decomposition, adaptive histogram equalization, and morphological filtering to improve image quality and feature clarity. The proposed NASNet-ViT model classifies lung images into five categories, normal, lung cancer, COVID-19, pneumonia, and tuberculosis achieving outstanding performance metrics: 98.9% accuracy, 0.99 sensitivity, 0.988 F1-score, and 0.985 specificity. Compared to established architectures such as MixNet-LD, D-ResNet, MobileNet, and ResNet50, NASNet-ViT demonstrates superior accuracy while maintaining a lightweight model size of only 25.6 MB and fast inference time of 12.4 seconds, making it practical for deployment in real-time, resource-constrained clinical environments. This research advances the field of medical image analysis by offering a robust and scalable AI solution capable of supporting clinicians in timely and precise lung disease diagnosis.
Authors
- Muhammad Zaheer Sajid (ORCID: https://orcid.org/0009-0005-5794-7902)
- Abida Sharif (ORCID: https://orcid.org/0000-0002-0409-3684)
- Jarrar Amjad
- Anwaar Ulhaq
- Sajjad Saleem
- Haya Aldossary
Institutions
- George Mason University (US)
- Kansas State University (US)
- United States Patent and Trademark Office (US)
- Wuyi University (CN)
- Central Queensland University (AU)
- Imam Abdulrahman Bin Faisal University (SA)
Publication Details
- Journal
- SLAS TECHNOLOGY
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1016/j.slast.2026.100394
- Citations
- 2
- Primary Topic
- COVID-19 diagnosis using AI
- Type
- article
- Field-Weighted Citation Impact
- 63.85