International Prognostic Scoring System, Revised International Prognostic Scoring System, and Molecular International Prognostic Scoring System Had No Identical Prognostic Power Depending on Treatment in Myelodysplastic Syndromes

The IPSS-M effectively reclassified 41.9% of patients, upstaging 20.2% and downstaging 21.7%. However, our analysis found that none of the prognostic scores effectively predicted outcomes for ESA-treated patients. Further studies are needed to assess whether the predictive value of these scoring systems is influenced by the specific treatment modalities used.

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Publication Details

Journal
Acta Haematologica
Published
2026-01-23
DOI
https://doi.org/10.1159/000549858
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

International Prognostic Scoring System, Revised International Prognostic Scoring System, and Molecular International Prognostic Scoring System Had No Identical Prognostic Power Depending on Treatment in Myelodysplastic Syndromes

Michael Loschi, Rinzine Sammut, T. Cluzeau, Sami Benachour et al.
Acta Haematologica
Acute Myeloid Leukemia Research
article

International Prognostic Scoring System, Revised International Prognostic Scoring System, and Molecular International Prognostic Scoring System Had No Identical Prognostic Power Depending on Treatment in Myelodysplastic Syndromes

Michael Loschi, Rinzine Sammut, T. Cluzeau, Sami Benachour, Neila De Pooter, Ghada Abichou, Bochra Sedaki, Joy Mouanes-Abelin, Corinne Ferrero-Vacher, Berengere Dadone-Montaudie, Caroline Fileni
article en

Abstract

The IPSS-M effectively reclassified 41.9% of patients, upstaging 20.2% and downstaging 21.7%. However, our analysis found that none of the prognostic scores effectively predicted outcomes for ESA-treated patients. Further studies are needed to assess whether the predictive value of these scoring systems is influenced by the specific treatment modalities used.

Acta Haematologica
Inserm (FR), Université Côte d'Azur (FR), Centre Hospitalier Universitaire de Nice (FR), Centre Méditerranéen de Médecine Moléculaire (FR)
Openalex Percentile: Top 82%
Acute Myeloid Leukemia Research
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