Plasma concentrations of IP-10 and MCP-1 as predictors of immunological non-response in people living with HIV receiving antiretroviral therapy

IP-10 and MCP-1 demonstrated strong predictive value for INR in PLHIV with low and high baseline CD4+ T cell counts, respectively. These cytokines may serve as valuable biomarkers for guiding individualized immune monitoring in ART-treated PLHIV.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2026-01-23
DOI
https://doi.org/10.1016/j.ijid.2026.108431
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Plasma concentrations of IP-10 and MCP-1 as predictors of immunological non-response in people living with HIV receiving antiretroviral therapy

Yingyin Yang, Xuemei Ling, Haisheng Yu, Linghua Li et al.
International Journal of Infectious Diseases
HIV Research and Treatment
article

Plasma concentrations of IP-10 and MCP-1 as predictors of immunological non-response in people living with HIV receiving antiretroviral therapy

Yingyin Yang, Xuemei Ling, Haisheng Yu, Linghua Li, Heping Zhao, Jingliang Chen, Fenqi Da, Fengyu Hu, Huijun Hou
article en

Abstract

IP-10 and MCP-1 demonstrated strong predictive value for INR in PLHIV with low and high baseline CD4+ T cell counts, respectively. These cytokines may serve as valuable biomarkers for guiding individualized immune monitoring in ART-treated PLHIV.

International Journal of Infectious DiseasesVol. 164
Guangzhou Eighth People's Hospital (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 80%
HIV Research and Treatment
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