A Karnofsky Performance Status-Based Risk Score Improves Prediction of Post-Sepsis Mortality in Sub-Saharan Africa: A Multicohort Study From Uganda
KPS assessed at hospital discharge significantly improves prediction of post-discharge mortality among acute sepsis survivors in sub-Saharan Africa. Incorporating KPS into discharge planning may help guide targeted interventions to improve sepsis survivorship in low- and middle-income countries.
Authors
- Joweria Nakaseegu (ORCID: https://orcid.org/0000-0001-9864-0679)
- Barnabas Bakamutumaho (ORCID: https://orcid.org/0000-0003-4259-8509)
- John Kayiwa (ORCID: https://orcid.org/0000-0002-1840-1801)
- Xiaoyu Che (ORCID: https://orcid.org/0000-0002-9738-7664)
- Alin S. Tomoiaga (ORCID: https://orcid.org/0000-0003-2221-8484)
- Devin Videlefsky
- S. Reynolds
- Irene Nayiga
- Martina Cathy Nakibuuka
- Nicholas Owor
- Stephen Kyebambe
- Max R. O’Donnell (ORCID: https://orcid.org/0000-0002-1232-3718)
- Joseph Shinyale
- Xuan Lu (ORCID: https://orcid.org/0009-0001-9863-0187)
- Jesse Ross (ORCID: https://orcid.org/0009-0008-3405-0897)
- J. Julius Lutwama
- Thomas Ochar
- Christopher Nsereko
- Ignatius Asasira
- Tonny Kiyingi
- Mercy Haumba
- Matthew J. Cummings
Institutions
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Busitema University (UG)
- Ministry of Agriculture, Animal Industry and Fisheries (UG)
- Rakai Health Sciences Program (UG)
- National Institute of Allergy and Infectious Diseases (US)
- Manhattan University (US)
- Columbia University (US)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2026-01-23
- DOI
- https://doi.org/10.1097/ccm.0000000000007036
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 31.52