Successful Treatment of Refractory Sweet's Syndrome With Adalimumab in a Myelodysplastic Syndrome Patient

We report a 69-year-old man diagnosed as myelodysplastic syndrome and administrated with azacitidine and selinexor treatment. Then he was revealed high fever and multiple tender erythematous papules involving his mouth, back, upper and lower extremities, which were diagnosed as Sweet's syndrome by skin biopsy. He was administrated with adalimumab and his rashes gradually disappeared after adalimumab treatment. But he had secondary disseminated fungal infections. Finally, he died of heart failure and severe infection. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

Authors

Institutions

Publication Details

Journal
eJHaem
Published
2026-01-22
DOI
https://doi.org/10.1002/jha2.70218
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Successful Treatment of Refractory Sweet's Syndrome With Adalimumab in a Myelodysplastic Syndrome Patient

Shanshan Suo, Jianjun Qiao, Weifang Zhu, L. Wang et al.
eJHaem
Autoimmune and Inflammatory Disorders
article

Successful Treatment of Refractory Sweet's Syndrome With Adalimumab in a Myelodysplastic Syndrome Patient

Shanshan Suo, Jianjun Qiao, Weifang Zhu, L. Wang, Yaojia Shen, Hongyan Tong, Jie Chang, Liya Ma
article en

Abstract

We report a 69-year-old man diagnosed as myelodysplastic syndrome and administrated with azacitidine and selinexor treatment. Then he was revealed high fever and multiple tender erythematous papules involving his mouth, back, upper and lower extremities, which were diagnosed as Sweet's syndrome by skin biopsy. He was administrated with adalimumab and his rashes gradually disappeared after adalimumab treatment. But he had secondary disseminated fungal infections. Finally, he died of heart failure and severe infection. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

eJHaemVol. 7(1)
Children's Hospital of Zhejiang University (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN), First Affiliated Hospital Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 80%
Autoimmune and Inflammatory Disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.