Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway

Formononetin shows potential as an anti-allergic agent by alleviating inflammatory responses in CIU through suppression of the TAK1/MAPK pathway in both murine models and MC/9 cells.

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Publication Details

Journal
PLoS ONE
Published
2026-01-23
DOI
https://doi.org/10.1371/journal.pone.0340078
Primary Topic
Urticaria and Related Conditions
Type
article
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0.00
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article

Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway

Yan Wu, Chunyu Li
PLoS ONE
Urticaria and Related Conditions
article

Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway

Yan Wu, Chunyu Li
article en

Abstract

Formononetin shows potential as an anti-allergic agent by alleviating inflammatory responses in CIU through suppression of the TAK1/MAPK pathway in both murine models and MC/9 cells.

PLoS ONEVol. 21(1)
Anhui University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 81%
Urticaria and Related Conditions
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Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway — Yan Wu, Chunyu Li · PLoS ONE (2026) | TGRS Research Map | TGRS