Antiviral Drug Discovery from Typha angustifolia Pollen: Computational Analysis Targeting Flaviviridae Polymerases and Entry Proteins

Naringenin emerged as the most potent and reliable antiviral agent among the compounds of T. angustifolia, particularly against the RdRp of Japanese encephalitis. These computational insights validate T. angustifolia pollen as a promising natural antiviral resource, warranting further validation through in vitro and in vivo studies.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2026-01-14
DOI
https://doi.org/10.2174/0113816128415696251113071814
Primary Topic
Mosquito-borne diseases and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Antiviral Drug Discovery from Typha angustifolia Pollen: Computational Analysis Targeting Flaviviridae Polymerases and Entry Proteins

Alvin R. Caparanga, Cheng‐Yang Hsieh, Po-Wei Tsai, Janielle Mari Abadilla et al.
Current Pharmaceutical Design
Mosquito-borne diseases and control
article

Antiviral Drug Discovery from Typha angustifolia Pollen: Computational Analysis Targeting Flaviviridae Polymerases and Entry Proteins

Alvin R. Caparanga, Cheng‐Yang Hsieh, Po-Wei Tsai, Janielle Mari Abadilla, Kristopher Ray Pamintuan, Bor-Yann Chen
article en

Abstract

Naringenin emerged as the most potent and reliable antiviral agent among the compounds of T. angustifolia, particularly against the RdRp of Japanese encephalitis. These computational insights validate T. angustifolia pollen as a promising natural antiviral resource, warranting further validation through in vitro and in vivo studies.

Current Pharmaceutical DesignVol. 32
Mapúa University (PH), National Taiwan Ocean University (TW), National Ilan University (TW)
Responsible consumption and production
Openalex Percentile: Top 81%
Mosquito-borne diseases and control
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