Antiviral Drug Discovery from Typha angustifolia Pollen: Computational Analysis Targeting Flaviviridae Polymerases and Entry Proteins
Naringenin emerged as the most potent and reliable antiviral agent among the compounds of T. angustifolia, particularly against the RdRp of Japanese encephalitis. These computational insights validate T. angustifolia pollen as a promising natural antiviral resource, warranting further validation through in vitro and in vivo studies.
Authors
- Alvin R. Caparanga
- Cheng‐Yang Hsieh (ORCID: https://orcid.org/0000-0002-8772-4073)
- Po-Wei Tsai
- Janielle Mari Abadilla
- Kristopher Ray Pamintuan
- Bor-Yann Chen
Institutions
- Mapúa University (PH)
- National Taiwan Ocean University (TW)
- National Ilan University (TW)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2026-01-14
- DOI
- https://doi.org/10.2174/0113816128415696251113071814
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00