Laser interstitial thermal therapy for IDH wild-type recurrent glioblastoma: a Scandinavian two-center cohort study

LITT was feasible and well tolerated in this two-center Scandinavian cohort, with short hospitalization and low morbidity. Survival outcomes were within the range reported in previous international series. While these findings provide preliminary real-world data on LITT use within Scandinavian publicly funded healthcare systems, the limited sample size and retrospective design preclude definitive conclusions. Prospective, controlled studies are warranted to clarify the clinical role of LITT in recurrent glioblastoma.

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Publication Details

Journal
Acta Neurochirurgica
Published
2026-01-23
DOI
https://doi.org/10.1007/s00701-026-06771-0
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Laser interstitial thermal therapy for IDH wild-type recurrent glioblastoma: a Scandinavian two-center cohort study

Thomas Urup, Margret Jensdottir, Sara Tabari, Silas Haahr Nielsen et al.
Acta Neurochirurgica
Glioma Diagnosis and Treatment
article

Laser interstitial thermal therapy for IDH wild-type recurrent glioblastoma: a Scandinavian two-center cohort study

Thomas Urup, Margret Jensdottir, Sara Tabari, Silas Haahr Nielsen, J Bartek, Rune Rasmussen, Adam E. Hansen, Jane Skjøth-Rasmussen
article en

Abstract

LITT was feasible and well tolerated in this two-center Scandinavian cohort, with short hospitalization and low morbidity. Survival outcomes were within the range reported in previous international series. While these findings provide preliminary real-world data on LITT use within Scandinavian publicly funded healthcare systems, the limited sample size and retrospective design preclude definitive conclusions. Prospective, controlled studies are warranted to clarify the clinical role of LITT in recurrent glioblastoma.

Acta NeurochirurgicaVol. 168(1)
University of Copenhagen (DK), Karolinska University Hospital (SE), Copenhagen University Hospital (DK), Rigshospitalet (DK), Karolinska Institutet (SE), Danish Cancer Society (DK)
Rigshospitalet
Partnerships for the goals
Openalex Percentile: Top 80%
Glioma Diagnosis and Treatment
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