The Pathophysiological Significance of Dual Inhibition of IL-17A and IL-17F in Psoriatic Arthritis and Axial Spondyloarthritis

Inhibiting both IL-17A and IL-17F signifies not only a significant therapeutic advancement but also a vital strategy towards overcoming the limitations of our current armamentarium in achieving deeper and more sustained remission in SpA. Future studies and long-term data will be essential in determining the position of dual IL-17A/F inhibitors within treatment guidelines.

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Publication Details

Journal
Mediterranean Journal of Rheumatology
Published
2026-01-21
DOI
https://doi.org/10.31138/mjr.020925.aar
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
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article

The Pathophysiological Significance of Dual Inhibition of IL-17A and IL-17F in Psoriatic Arthritis and Axial Spondyloarthritis

Andreas V. Goules, O. Katsouli, V. Lainis, Panayiotis G. Vlachoyiannopoulos
Mediterranean Journal of Rheumatology
Spondyloarthritis Studies and Treatments
article

The Pathophysiological Significance of Dual Inhibition of IL-17A and IL-17F in Psoriatic Arthritis and Axial Spondyloarthritis

Andreas V. Goules, O. Katsouli, V. Lainis, Panayiotis G. Vlachoyiannopoulos
article en

Abstract

Inhibiting both IL-17A and IL-17F signifies not only a significant therapeutic advancement but also a vital strategy towards overcoming the limitations of our current armamentarium in achieving deeper and more sustained remission in SpA. Future studies and long-term data will be essential in determining the position of dual IL-17A/F inhibitors within treatment guidelines.

Mediterranean Journal of RheumatologyVol. 37(Suppl 1)
National and Kapodistrian University of Athens (GR)
Good health and well-being
Openalex Percentile: Top 81%
Spondyloarthritis Studies and Treatments
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