Diagnostic utility of <scp>APRI</scp> , <scp>FIB</scp> ‐4, and <scp>FIB</scp> ‐5 in intrahepatic cholestasis of pregnancy: A retrospective case–control study

APRI, FIB-4, and FIB-5 are elevated in pregnancies affected by ICP and may serve as supportive, non-invasive markers reflecting hepatocellular stress and hepatic involvement. Among these indices, APRI showed the best diagnostic performance, FIB-5 demonstrated moderate discriminative ability, and FIB-4 had limited diagnostic utility. These indices may provide clinicians with additional information when evaluating hepatic dysfunction and may be associated with neonatal outcomes, although they are not validated prognostic tools. Prospective studies are warranted to further validate their clinical utility.