Exploring the toxicity mechanisms of acetyl tributyl citrate in premature ovarian insufficiency via network toxicology and molecular docking
This integrative study sheds light on the molecular mechanisms by which ATBC may contribute to POI. By identifying critical targets and pathways, our findings provide a foundation for further toxicological research and underscore the utility of combining computational prediction, network analysis to assess the reproductive risks of environmental contaminants.
Authors
- Xianlai Duan (ORCID: https://orcid.org/0000-0002-4627-6796)
- Sumei Xu (ORCID: https://orcid.org/0000-0002-0297-7208)
Institutions
- Central South University (CN)
- National Clinical Research (US)
- Xiangya Hospital Central South University (CN)
- Third Hospital of Changsha (CN)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Drug and Chemical Toxicology
- Published
- 2026-01-23
- DOI
- https://doi.org/10.1080/01480545.2026.2617228
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00