<scp>SGLT2</scp> inhibitors and mortality in older adults with diabetic kidney disease: A target trial emulation study
In this target trial emulation study, SGLT2 inhibitors were associated with lower mortality in older adults with DKD, particularly those under 80 years and with BMI ≥22 kg/m<sup>2</sup>. These findings support personalized treatment decisions for this high-risk population in clinical practice.
Authors
- Kaori Hayashi (ORCID: https://orcid.org/0000-0002-9020-3068)
- Kazuki Aoyama
- N. Takeda
- T. Yokoo
- Katsuhiko Fujiu
- M. Nangaku
- Y Kimura
- Toshiyuki Ko (ORCID: https://orcid.org/0000-0002-9043-064X)
- Hideo Yasunaga (ORCID: https://orcid.org/0000-0002-6017-469X)
- Koichi Node
- Hidehiro Kaneko
- Norihiko Takeda
- Yuta Suzuki
- Takashin Nakayama
- Hiroyuki Morita
- Tatsuhiko Azegami
- Akira Okada
Institutions
- Jikei University School of Medicine (JP)
- Saga University (JP)
- Keio University (JP)
- National Institute of Public Health (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-01-23
- DOI
- https://doi.org/10.1111/dom.70502
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Tokyo