Combination of Metronomic Chemotherapy and Rituximab in Frail and Elderly Patients with Relapsed/Refractory Follicular Lymphoma and Ineligible for Lenalidomide Treatment: A Retrospective Analysis

Metronomic R-DEVEC-light is a feasible and effective disease-controlling strategy for frail, heavily pretreated rrFL patients who do not tolerate lenalidomide and are excluded from modern therapies. This schedule warrants further prospective evaluation and exploration in combination with targeted agents.

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Publication Details

Journal
Cancers
Published
2026-01-22
DOI
https://doi.org/10.3390/cancers18020347
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

Combination of Metronomic Chemotherapy and Rituximab in Frail and Elderly Patients with Relapsed/Refractory Follicular Lymphoma and Ineligible for Lenalidomide Treatment: A Retrospective Analysis

Lucrezia De Marchi, Marta Banchi, Emanuele Cencini, Andrea Nunzi et al.
Cancers
Lymphoma Diagnosis and Treatment
article

Combination of Metronomic Chemotherapy and Rituximab in Frail and Elderly Patients with Relapsed/Refractory Follicular Lymphoma and Ineligible for Lenalidomide Treatment: A Retrospective Analysis

Lucrezia De Marchi, Marta Banchi, Emanuele Cencini, Andrea Nunzi, Guido Bocci, Claudia Seimonte, Susanna Destefano, Maria Christina Cox, Alberto Fabbri, Sabrina Pelliccia
article en

Abstract

Metronomic R-DEVEC-light is a feasible and effective disease-controlling strategy for frail, heavily pretreated rrFL patients who do not tolerate lenalidomide and are excluded from modern therapies. This schedule warrants further prospective evaluation and exploration in combination with targeted agents.

CancersVol. 18(2)
University of Pisa (IT), University of Rome Tor Vergata (IT), Azienda Ospedaliera Sant'Andrea (IT), Azienda Ospedaliera Universitaria Senese (IT), Policlinico Tor Vergata (IT)
Good health and well-being
Openalex Percentile: Top 81%
Lymphoma Diagnosis and Treatment
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Combination of Metronomic Chemotherapy and Rituximab in Frail and Elderly Patients with Relapsed/Refractory Follicular Lymphoma and Ineligible for Lenalidomide Treatment: A Retrospective Analysis — Lucrezia De Marchi, Marta Banchi, et al. · Cancers (2026) | TGRS Research Map | TGRS