Borrelia mayonii induces carditis but not arthritis in Lyme-susceptible mice
Taken together, this study characterizes similarities and differences between <i>B. burgdorferi</i> and <i>B. mayonii</i> in a laboratory model of Lyme disease. These findings add to the immunopathologic landscape caused by distinct genospecies in the Bbsl complex, which could shed light on the distinct host-pathogen interactions important for specific Lyme disease manifestations.
Authors
- Heidi L. Pecoraro (ORCID: https://orcid.org/0000-0001-5475-5482)
- Dawn W. Cleveland (ORCID: https://orcid.org/0000-0002-9963-5123)
- Catherine A. Brissette (ORCID: https://orcid.org/0000-0003-0792-1403)
- Timothy Casselli (ORCID: https://orcid.org/0000-0003-1954-2443)
- Yvonne Tourand (ORCID: https://orcid.org/0000-0002-4751-6683)
- Nivanthi Wijetunga
Institutions
- Dakota State University (US)
- University of North Dakota (US)
- North Dakota State University (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.3389/fimmu.2026.1727413
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Allergy and Infectious Diseases