Low-Dose Aspirin Continuation During Gastric Endoscopic Submucosal Dissection in Patients With Low Thrombotic Risk: A Randomized Trial

The noninferiority of LDA continuation over discontinuation for ESD-related major bleeding in gastric ESD was not demonstrated. Therefore, discontinuation of LDA during the periprocedural period is recommended for patients with low thrombotic risk (UMIN000013177).

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Journal
The American Journal of Gastroenterology
Published
2026-01-22
DOI
https://doi.org/10.14309/ajg.0000000000003928
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
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article

Low-Dose Aspirin Continuation During Gastric Endoscopic Submucosal Dissection in Patients With Low Thrombotic Risk: A Randomized Trial

Noriya Uedo, Koichi Kawabe, Akihiro MATSUDA, Shoichi Kayaba et al.
The American Journal of Gastroenterology
Gastric Cancer Management and Outcomes
article

Low-Dose Aspirin Continuation During Gastric Endoscopic Submucosal Dissection in Patients With Low Thrombotic Risk: A Randomized Trial

Noriya Uedo, Koichi Kawabe, Akihiro MATSUDA, Shoichi Kayaba, Takuji Akamatsu, Yasuaki Nagami, Takeshi Yamashina, Kohei Takizawa, Hisashi Doyama, Kiyotaka Umeki, Tetsu Arai, Yoshimasa Miura, Ichiro Oda, Takuji Gotoda, Toshiyuki Yoshio, Satoshi Ono, Hideki Ishikawa, Yoshinobu Yamamoto, Kenshi Matsumoto, for the SET-UP Trial Group, Osamu Dohi
article en

Abstract

The noninferiority of LDA continuation over discontinuation for ESD-related major bleeding in gastric ESD was not demonstrated. Therefore, discontinuation of LDA during the periprocedural period is recommended for patients with low thrombotic risk (UMIN000013177).

The American Journal of Gastroenterology
Nihon University (JP), Jichi Medical University (JP), Osaka City University (JP), Juntendo University (JP), Kyoto Prefectural University of Medicine (JP), National Cancer Centre Japan (JP), Toyama Prefectural Central Hospital (JP), Shizuoka Cancer Center (JP), Iwate Prefectural Central Hospital (JP), Fukui Red Cross Hospital (JP), Chiba-Nishi General Hospital (JP), Ishikawa Prefectural Central Hospital (JP), Osaka International Cancer Institute (JP), Osaka Red Cross Hospital (JP), Japanese Red Cross Society Wakayama Medical Center (JP), Hyogo Prefectural Cancer Center (JP), Hirosaki University Hospital (JP), Japanese Foundation For Cancer Research (JP), The University of Tokyo (JP)
Good health and well-being
Openalex Percentile: Top 81%
Gastric Cancer Management and Outcomes
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