Bioactive Phytochemicals: Sources, Production, and Delivery of Betalains, Carotenoids, Organosulfur Compounds, Phenolics, and Phytosterols
Bioactive compounds are naturally occurring food constituents with potentially health-promoting properties, although no official daily intake recommendations have currently been established for them. Among these, phytochemicals-such as betalains, carotenoids, organosulfur compounds, phenolics, and phytosterols-stand out due to their biological relevance. Interdisciplinary collaboration is crucial for advancing phytochemical research, from identifying novel sources and optimizing production to evaluating their biological functions and potential applications. This review summarizes conventional and emerging sources of these key phytochemicals, including wild edible plants, microorganisms, algae, insects, and food industry by-products, emphasizing their potential under sustainability and climate change contexts. Advances in extraction technologies and the use of green solvents are also discussed. Furthermore, genetic and agronomic strategies to enhance bioactive content are considered. The article also addresses formulation approaches focused on delivery systems to improve dispersibility, stability, and bioavailability.
Authors
- Diego A. Moreno (ORCID: https://orcid.org/0000-0002-6547-8764)
- F. Shahidi
- Renan Danielski (ORCID: https://orcid.org/0009-0000-1972-8243)
- Pedro Ariel Martínez-Rodríguez
- Daniela Andrea Ramírez (ORCID: https://orcid.org/0000-0002-8581-6644)
- Antonio J. Meléndez‐Martínez (ORCID: https://orcid.org/0000-0002-1553-2427)
- Alejandra B. Camargo (ORCID: https://orcid.org/0000-0001-9749-8842)
- Antonio Cilla (ORCID: https://orcid.org/0000-0001-6532-9032)
- Fernando Gandía‐Herrero (ORCID: https://orcid.org/0000-0003-4389-3454)
- Vanesa Núñez-Gómez
- Guadalupe Garcia-Llatas
- Paula Mapelli-Brahm
- David Julian McClements
Institutions
- Memorial University of Newfoundland (CA)
- Universidad Nacional de Cuyo (AR)
- Universitat de València (ES)
- University of Massachusetts Amherst (US)
- Centro de Edafología y Biología Aplicada del Segura (ES)
- Instituto de Biología Agrícola de Mendoza (AR)
- Centro Científico Tecnológico - Mendoza (AR)
- Universidad de Sevilla (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- Annual Review of Food Science and Technology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1146/annurev-food-060424-091706
- Primary Topic
- Botanical Research and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00