Diffuse Infiltration of both Breasts in Pregnant Women is the First Manifestation of Myeloid Sarcoma - A Case Report and Literature Review

Myeloid sarcoma (MS) during pregnancy is rare, and cases initially presenting as bilateral breast infiltration are particularly misleading and difficult to diagnose. It is essential to differentiate MS from conditions such as mammary hyperplasia and breast cancer. We report a case of a 28-year-old woman who developed bilateral breast induration, distension, and serous discharge at seven months’ gestation. The final diagnosis was MS secondary to acute myeloid leukemia. The patient is currently undergoing chemotherapy. Clinicians should increase their awareness of MS and, when necessary, recommend hematological and bone marrow cytomorphological examinations for pregnant women presenting with suspicious breast symptoms to ensure early diagnosis.

Authors

Publication Details

Journal
Journal of Oncological Sciences
Published
2026-01-22
DOI
https://doi.org/10.37047/jos.galenos.2025.2025-10-2
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
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article

Diffuse Infiltration of both Breasts in Pregnant Women is the First Manifestation of Myeloid Sarcoma - A Case Report and Literature Review

Wei Yang, Chendong HE
Journal of Oncological Sciences
Cancer Risks and Factors
article

Diffuse Infiltration of both Breasts in Pregnant Women is the First Manifestation of Myeloid Sarcoma - A Case Report and Literature Review

Wei Yang, Chendong HE
article en

Abstract

Myeloid sarcoma (MS) during pregnancy is rare, and cases initially presenting as bilateral breast infiltration are particularly misleading and difficult to diagnose. It is essential to differentiate MS from conditions such as mammary hyperplasia and breast cancer. We report a case of a 28-year-old woman who developed bilateral breast induration, distension, and serous discharge at seven months’ gestation. The final diagnosis was MS secondary to acute myeloid leukemia. The patient is currently undergoing chemotherapy. Clinicians should increase their awareness of MS and, when necessary, recommend hematological and bone marrow cytomorphological examinations for pregnant women presenting with suspicious breast symptoms to ensure early diagnosis.

Journal of Oncological Sciences
Gender equality
Openalex Percentile: Top 80%
Cancer Risks and Factors
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Diffuse Infiltration of both Breasts in Pregnant Women is the First Manifestation of Myeloid Sarcoma - A Case Report and Literature Review — Wei Yang, Chendong HE · Journal of Oncological Sciences (2026) | TGRS Research Map | TGRS