Long-term Indian optic neuritis study (THE LION STUDY): clinical, imaging features and visual behavior of optic neuritis in Indian population over two decades

This ON study group of the Indian population had more optic disc edema on presentation and visual outcomes similar to those of other Asian studies, unlike ONTT. Idiopathic ON and neuromyelitis optica spectrum disorder-optic neuritis (NMOSD-ON) were more common than MS optic neuritis (MS-ON) in this cohort population. Prospective long-term follow-up of these patients can reveal the natural disease course, neurological associations, and treatment outcomes.