Metabolomic Markers of Left Ventricular Structure, Diastolic Function, and Risk of Coronary Heart Disease: A Longitudinal Study in American Indian Individuals

We identified metabolomic markers of LV structure and diastolic function, several of which that were independently associated with CHD risk, providing insight into metabolic pathways underlying LV subclinical changes and CHD.

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Publication Details

Journal
Journal of the American Heart Association
Published
2026-01-22
DOI
https://doi.org/10.1161/jaha.125.044310
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
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article

Metabolomic Markers of Left Ventricular Structure, Diastolic Function, and Risk of Coronary Heart Disease: A Longitudinal Study in American Indian Individuals

Mingjing Chen, Guanhong Miao, Tanika N Kelly, SA Cole et al.
Journal of the American Heart Association
Metabolomics and Mass Spectrometry Studies
article

Metabolomic Markers of Left Ventricular Structure, Diastolic Function, and Risk of Coronary Heart Disease: A Longitudinal Study in American Indian Individuals

Mingjing Chen, Guanhong Miao, Tanika N Kelly, SA Cole, Jason G. Umans, Yixi Sun, Oliver Fiehn, Mario Roman, Camilo Fernandez, Richard R. Fabsitz, Alexander C. Razavi, Ying Zhang, Xiaoxiao Wen, Jinying Zhao, Richard B. Devereux, Lydia A. Bazzano
article en

Abstract

We identified metabolomic markers of LV structure and diastolic function, several of which that were independently associated with CHD risk, providing insight into metabolic pathways underlying LV subclinical changes and CHD.

Journal of the American Heart AssociationVol. 15(3)
Tulane University (US), Texas Biomedical Research Institute (US), Johns Hopkins University (US), Emory University (US), Cornell University (US), University of South Florida (US), University of Illinois Chicago (US), Georgetown-Howard Universities Center for Clinical and Translational Science (US), Missouri Breaks Industries Research (United States) (US), University of Oklahoma Health Sciences Center (US), University of California, Davis (US), MedStar Health (US)
Good health and well-being
Openalex Percentile: Top 81%
Metabolomics and Mass Spectrometry Studies
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