Impact of Sperm Retrieval Yield and Freezing on ICSI Outcomes in Non‐Obstructive Azoospermia: A Retrospective Study of 1394 Micro‐TESE Cycles

Sperm retrieval quantity is an important predictor of intracytoplasmic sperm injection success in men with non-obstructive azoospermia. Freezing generally does not affect outcomes, but may significantly reduce live birth rates when sperm availability is extremely limited. Prioritizing the use of fresh spermatozoa in such cases may improve clinical outcomes.

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Publication Details

Journal
Andrology
Published
2026-01-21
DOI
https://doi.org/10.1111/andr.70180
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of Sperm Retrieval Yield and Freezing on ICSI Outcomes in Non‐Obstructive Azoospermia: A Retrospective Study of 1394 Micro‐TESE Cycles

Kai Hong, Qingqing Tao, Xiulian Ren, Rong Li et al.
Andrology
Sperm and Testicular Function
article

Impact of Sperm Retrieval Yield and Freezing on ICSI Outcomes in Non‐Obstructive Azoospermia: A Retrospective Study of 1394 Micro‐TESE Cycles

Kai Hong, Qingqing Tao, Xiulian Ren, Rong Li, Li Lei, Ming Li, Ping Liu, Jin Huang, Ying Lian, Qin Li
article en

Abstract

Sperm retrieval quantity is an important predictor of intracytoplasmic sperm injection success in men with non-obstructive azoospermia. Freezing generally does not affect outcomes, but may significantly reduce live birth rates when sperm availability is extremely limited. Prioritizing the use of fresh spermatozoa in such cases may improve clinical outcomes.

Andrology
Peking University (CN), National Clinical Research Center for Digestive Diseases (CN), Ministry of Education (RO), CARE Fertility (US), Peking University Third Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 82%
Sperm and Testicular Function
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