Association of Laryngeal Squamous Cell Carcinoma and Papillary Thyroid Carcinoma: A Case Series of Four Patients

Abstract The synchronous occurrence of laryngeal squamous cell carcinoma (LSCC) and papillary thyroid carcinoma (PTC) is rare and is most often discovered incidentally on histopathological examination of surgical specimens. We report a series of four cases illustrating this uncommon association, focusing on clinical presentation, histological findings, therapeutic management, and outcomes. Prognosis mainly depends on the laryngeal squamous cell carcinoma, while papillary thyroid carcinoma generally exhibits favorable behavior. In the absence of standardized management guidelines, a multidisciplinary and individualized therapeutic approach is essential.