Factors influencing suicidal ideation in Chinese adolescents with first-episode depressive disorder: a cross-sectional study

Given the high prevalence and severe consequences of suicidal ideation (SI) in adolescents, it is critical to identify multidimensional predictors of the illness. This study aimed to investigate the physiological, psychological, and sociological factors that influence SI in adolescents with first-episode depressive disorder. The study was recruited through convenience sampling. Data were collected using self-designed questionnaires, the Hamilton Depression Scale 24-item, the Hamilton Anxiety Scale, and the Simplified Coping Style Questionnaire. Thyroid function, cortisol, lipids, and event-related potential were measured in the participants. All independent variables were included in the model for logistic regression. Statistical analysis of data was done using SPSS version 25.0. The present study was for the inclusion of 150 adolescents who presented with first-episode depressive disorder, of whom 96 (64.00%) had SI. Females and older adolescents were more prone to SI. Depressive symptoms, anxiety symptoms, negative coping styles, total cholesterol levels, and the latency of P3a and P3b were positively correlated with SI. Positive coping style, N2 amplitude, and SI were negatively correlated. SI in Chinese adolescents with first-episode depressive disorder demonstrates a multifactorial relationship, involving physiological, psychological, and sociological factors. It is necessary to conduct multidomain, comprehensive assessments and develop intervention strategies.