Cost-Effectiveness of Adjuvant Immunotherapy in Cancer Treatments

This systematic review found that adjuvant immunotherapy was frequently associated with meaningful QALY/LY improvements and was often considered cost-effective in high-risk or first-line settings. However, economic value remains context-specific, shaped by treatment strategy, drug costs, and modeling assumptions. These findings support the selective, value-based adoption of adjuvant immunotherapy and underscore the need for transparent, standardized economic evaluations to guide reimbursement and policy decisions.

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Publication Details

Journal
JAMA Oncology
Published
2026-01-22
DOI
https://doi.org/10.1001/jamaoncol.2025.6080
Primary Topic
Immunotherapy and Immune Responses
Type
article
Field-Weighted Citation Impact
0.00
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article

Cost-Effectiveness of Adjuvant Immunotherapy in Cancer Treatments

Padam Kanta Dahal, Rashidul Alam Mahumud, Khorshed Alam, Yifu Chen et al.
JAMA Oncology
Immunotherapy and Immune Responses
article

Cost-Effectiveness of Adjuvant Immunotherapy in Cancer Treatments

Padam Kanta Dahal, Rashidul Alam Mahumud, Khorshed Alam, Yifu Chen, Md Shahjalal
article en

Abstract

This systematic review found that adjuvant immunotherapy was frequently associated with meaningful QALY/LY improvements and was often considered cost-effective in high-risk or first-line settings. However, economic value remains context-specific, shaped by treatment strategy, drug costs, and modeling assumptions. These findings support the selective, value-based adoption of adjuvant immunotherapy and underscore the need for transparent, standardized economic evaluations to guide reimbursement and policy decisions.

JAMA OncologyVol. 12(3)
The University of Sydney (AU), North South University (BD), University of Southern Queensland (AU), National Health and Medical Research Council (AU), Central Queensland University (AU)
Openalex Percentile: Top 80%
Immunotherapy and Immune Responses
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