Cost-Effectiveness of Adjuvant Immunotherapy in Cancer Treatments
This systematic review found that adjuvant immunotherapy was frequently associated with meaningful QALY/LY improvements and was often considered cost-effective in high-risk or first-line settings. However, economic value remains context-specific, shaped by treatment strategy, drug costs, and modeling assumptions. These findings support the selective, value-based adoption of adjuvant immunotherapy and underscore the need for transparent, standardized economic evaluations to guide reimbursement and policy decisions.
Authors
- Padam Kanta Dahal (ORCID: https://orcid.org/0000-0002-5978-3762)
- Rashidul Alam Mahumud (ORCID: https://orcid.org/0000-0001-9788-1868)
- Khorshed Alam (ORCID: https://orcid.org/0000-0002-6003-6991)
- Yifu Chen
- Md Shahjalal
Institutions
- The University of Sydney (AU)
- North South University (BD)
- University of Southern Queensland (AU)
- National Health and Medical Research Council (AU)
- Central Queensland University (AU)
Publication Details
- Journal
- JAMA Oncology
- Published
- 2026-01-22
- DOI
- https://doi.org/10.1001/jamaoncol.2025.6080
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00