Clinical Outcomes of Ticagrelor versus Clopidogrel in Patients with Chronic Kidney Disease and Acute Myocardial Infarction: A Real-World Cohort Study

In CKD patients with AMI, ticagrelor was associated with reduced all-cause mortality compared to clopidogrel, without an increased risk of major bleeding. These findings highlight the need for further prospective studies to confirm ticagrelor's benefits and inform optimal antiplatelet strategies in this high-risk population.

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Publication Details

Journal
Cardiorenal Medicine
Published
2026-01-22
DOI
https://doi.org/10.1159/000550521
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical Outcomes of Ticagrelor versus Clopidogrel in Patients with Chronic Kidney Disease and Acute Myocardial Infarction: A Real-World Cohort Study

Ching-Chung Hsiao, Wei-Chiao Sun, Lin Cc, Chieh-Li Yen et al.
Cardiorenal Medicine
Antiplatelet Therapy and Cardiovascular Diseases
article

Clinical Outcomes of Ticagrelor versus Clopidogrel in Patients with Chronic Kidney Disease and Acute Myocardial Infarction: A Real-World Cohort Study

Ching-Chung Hsiao, Wei-Chiao Sun, Lin Cc, Chieh-Li Yen, Shu-Chun Huang, Hsin-Fu Lee, Wen-Yu Ho, Jia-Jin Chen
article en

Abstract

In CKD patients with AMI, ticagrelor was associated with reduced all-cause mortality compared to clopidogrel, without an increased risk of major bleeding. These findings highlight the need for further prospective studies to confirm ticagrelor's benefits and inform optimal antiplatelet strategies in this high-risk population.

Cardiorenal MedicineVol. 16(1)
Chang Gung University of Science and Technology (TW), Chang Gung University (TW), Chang Gung Memorial Hospital (TW), Taipei Municipal YangMing Hospital (TW), Linkou Chang Gung Memorial Hospital (TW), Taipei City Hospital (TW)
Chang Gung Medical Foundation, Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Center for Big Data Analytics, University of Texas at Austin
Good health and well-being
Openalex Percentile: Top 82%
Antiplatelet Therapy and Cardiovascular Diseases
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