Targeting CD27 Boosts Vaccine-induced Immune Memory

A recent study shows that CD27 agonism can improve the efficacy and durability of vaccine-induced antitumor responses in HER2+ breast cancer. The outcomes may pave the way for approaches to improve the efficacy and durability of tumor antigen vaccines.

Publication Details

Journal
Cancer Discovery
Published
2026-01-21
DOI
https://doi.org/10.1158/2159-8290.cd-nw2026-0004
Primary Topic
Immunotherapy and Immune Responses
Type
article
Field-Weighted Citation Impact
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article

Targeting CD27 Boosts Vaccine-induced Immune Memory

Cancer Discovery
Immunotherapy and Immune Responses
article

Targeting CD27 Boosts Vaccine-induced Immune Memory

article en

Abstract

A recent study shows that CD27 agonism can improve the efficacy and durability of vaccine-induced antitumor responses in HER2+ breast cancer. The outcomes may pave the way for approaches to improve the efficacy and durability of tumor antigen vaccines.

Cancer DiscoveryVol. 16(3)
Good health and well-being
Openalex Percentile: Top 80%
Immunotherapy and Immune Responses
DOISourceOpenAlex
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Targeting CD27 Boosts Vaccine-induced Immune Memory · Cancer Discovery (2026) | TGRS Research Map | TGRS